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(9S)-9-[[[4-(Acetylamino)Phenyl]Sulfonyl]Amino]-9-Deoxoerythromycin CAS NO 57049-06-6


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CAS No.:57049-06-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(9S)-9-[[[4-(Acetylamino)Phenyl]Sulfonyl]Amino]-9-Deoxoerythromycin is a chemically modified derivative of the macrolide antibiotic erythromycin, designed for enhanced stability and targeted pharmacological activity. This semi-synthetic compound is critical for pharmaceutical research and development, particularly in the study of advanced antibacterial agents and their mechanisms of action. It serves as a key intermediate and reference standard for laboratories and manufacturers in the pharmaceutical and biotechnology sectors, where precise chemical structure and high purity are paramount.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel macrolide antibiotics and investigational drugs.
  • Biochemical Research: Used as a reference standard in studies of bacterial protein synthesis inhibition and antibiotic resistance mechanisms.
  • Analytical Standard: Employed in quality control laboratories for method development, validation, and calibration in HPLC and LC-MS analyses.
  • Antibacterial Agent Development: Acts as a lead compound for modifying and improving the pharmacokinetic and pharmacodynamic properties of erythromycin derivatives.
  • Academic Research: Utilized in university and institutional labs for microbiological and pharmacological research projects.

Basic Information

Product Name (9S)-9-[[[4-(Acetylamino)Phenyl]Sulfonyl]Amino]-9-Deoxoerythromycin
CAS No. 57049-06-6
Molecular Formula C41H67N3O13S
Molecular Weight 842.05 g/mol
Synonyms 9-Deoxo-9a-[[[4-(acetylamino)phenyl]sulfonyl]amino]erythromycin; Erythromycin 9-[[[4-(Acetylamino)phenyl]sulfonyl]amino]-9-deoxo-; 9(S)-9-[[[4-(Acetylamino)Phenyl]Sulfonyl]Amino]-9-Deoxoerythromycin; N-[(9S)-9-Amino-9-deoxoerythromycinyl]-4-acetamidobenzenesulfonamide; ABT-773 Intermediate
EINECS Contact for details

Quality Control

Our (9S)-9-[[[4-(Acetylamino)Phenyl]Sulfonyl]Amino]-9-Deoxoerythromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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