Description

1-Bromo-2-Chloro-3-Iodobenzene is a highly functionalized, multi-halogenated aromatic building block of significant synthetic utility. This compound is valued for its versatility in facilitating complex molecular transformations, particularly in the synthesis of advanced pharmaceutical intermediates and specialty organic materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring complex halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where specific halogen substitution patterns are critical for bioactivity.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and other functional organic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the differential reactivity of its bromo, chloro, and iodo substituents.
• Chemical Library Development: Employed in combinatorial and medicinal chemistry for the rapid generation of diverse compound libraries.
• Ligand and Catalyst Synthesis: Used to create sophisticated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	1-Bromo-2-Chloro-3-Iodobenzene
CAS No.	57012-50-7
Molecular Formula	C6H3BrClI
Molecular Weight	317.35 g/mol
Synonyms	2-Chloro-1-bromo-3-iodobenzene; 3-Iodo-1-bromo-2-chlorobenzene; Benzene, 1-bromo-2-chloro-3-iodo-; 1-Bromo-2-chloro-3-iodo-benzene; 2-Chloro-3-iodobromobenzene; 3-Bromo-2-chloroiodobenzene (numbering variant); BCIB (abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3-Iodobenzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP manufacturing for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and decomposition. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Reported value provided
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.