Description

(9S)-9-[[(4-Bromophenyl)Sulfonyl]Amino]-9-Deoxoerythromycin is a chemically modified derivative of the macrolide antibiotic erythromycin, designed for enhanced pharmacological research and development. This compound is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antibacterial agents. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel macrolide antibiotic derivatives.
• Antibacterial Research: Used in biological and microbiological studies to investigate structure-activity relationships (SAR) against resistant pathogens.
• API Development: Acts as a potential active pharmaceutical ingredient in the formulation development of new antibacterial drugs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Medicinal Chemistry: Utilized in lead optimization and drug discovery programs targeting bacterial protein synthesis inhibition.

Basic Information

Product Name	(9S)-9-[[(4-Bromophenyl)Sulfonyl]Amino]-9-Deoxoerythromycin
CAS No.	56998-48-2
Molecular Formula	C37H67BrN2O12S
Molecular Weight	843.91 g/mol
Synonyms	9-Deoxo-9-[(p-bromophenyl)sulfonyl]aminoerythromycin; Erythromycin 9-[(4-bromophenyl)sulfonyl]imine derivative; 9(S)-N-[(4-Bromophenyl)sulfonyl]erythromycylamine; 9-Deoxo-9a-aza-9a-homoerythromycin A 9a-N-[(4-bromophenyl)sulfonyl]; (9S)-9-Amino-9-deoxoerythromycin 4-bromobenzenesulfonamide; BPSA-Erythromycin; 56998-48-2
EINECS	Contact for details

Quality Control

Our (9S)-9-[[(4-Bromophenyl)Sulfonyl]Amino]-9-Deoxoerythromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay	97.0% - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.