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(R,R)-(-)-1,2-Bis[(o-Methoxyphenyl)(Phenyl)Phosphino]Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate CAS NO 56977-92-5
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CAS No.:56977-92-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R,R)-(-)-1,2-Bis[(o-Methoxyphenyl)(Phenyl)Phosphino]Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-value, chiral transition metal complex widely recognized as a highly efficient and enantioselective catalyst. Its core value proposition lies in enabling precise asymmetric synthesis, which is critical for producing single-enantiomer intermediates in pharmaceutical and fine chemical manufacturing. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for hydrogenation and other asymmetric transformations.
Application
- Asymmetric Hydrogenation Catalyst: Employed as a premier catalyst for the enantioselective hydrogenation of dehydroamino acid derivatives, enamides, and other prochiral substrates to produce chiral amino acids and amines.
- Pharmaceutical Intermediate Synthesis: Critical in the synthesis of single-enantiomer active pharmaceutical ingredients (APIs), where chirality dictates biological activity and safety profile.
- Agrochemical Production: Used in the manufacture of chiral herbicides, fungicides, and pesticides to enhance efficacy and reduce environmental impact.
- Fine Chemical and Fragrance Manufacturing: Facilitates the production of enantiomerically pure compounds for high-value flavors, fragrances, and specialty chemicals.
- Academic and Industrial R&D: A standard reagent in research laboratories for developing new asymmetric synthetic methodologies and catalytic processes.
- Process Chemistry Optimization: Implemented in scale-up and pilot plant studies to establish robust, high-yielding commercial manufacturing routes for chiral molecules.
Basic Information
| Product Name | (R,R)-(-)-1,2-Bis[(o-Methoxyphenyl)(Phenyl)Phosphino]Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate |
| CAS No. | 56977-92-5 |
| Molecular Formula | C46H46BF4O2P2Rh |
| Molecular Weight | 866.51 g/mol |
| Synonyms | (R,R)-(-)-DIPAMP-Rh(COD)BF4; (R,R)-(-)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; Rhodium(I)-(R,R)-(-)-1,2-Bis(o-anisylphenylphosphino)ethane(1,5-cyclooctadiene) tetrafluoroborate; (R,R)-DIPAMP Rhodium(I) Cyclooctadiene Tetrafluoroborate; [Rh((R,R)-DIPAMP)(COD)]BF4; (R,R)-DIPAMP-Rh Catalyst; Asymmetric Hydrogenation Catalyst with DIPAMP Ligand |
| EINECS | Contact for details |
Quality Control
Every batch of our (R,R)-(-)-DIPAMP-Rh(COD)BF4 catalyst is manufactured and tested under strict quality management systems. We guarantee high chemical purity and enantiomeric excess to meet the rigorous demands of process chemistry and cGMP environments where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, chiral purity, and identity confirmation via spectroscopic methods.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep the container sealed in a cool, dry, and well-ventilated place. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Rhodium Content | 11.5 - 12.2 % |
| Specific Rotation [α]D20 | -80° to -90° (c=1 in CH2Cl2) |
| Solubility | Soluble in dichloromethane, chloroform; slightly soluble in methanol, acetone |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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