Description

2-Chloro-3-Hydroxybenzaldehyde is a versatile aromatic aldehyde derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique substitution pattern, which allows for the selective introduction of both aldehyde and phenolic functionalities into target molecules. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex intermediates, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators due to its bioactive phenolic-chloro motif.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Intermediate for producing azo dyes and other complex colorants requiring specific light-fastness and hue properties.
• Flavor and Fragrance Chemistry: Building block for synthesizing specialized aromatic compounds used in high-value fragrance compositions.
• Polymer Modification: Employed to introduce aldehyde functional groups into polymer chains for cross-linking or further chemical modification.
• Academic and Contract Research: Essential reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2-Chloro-3-Hydroxybenzaldehyde
CAS No.	56962-10-8
Molecular Formula	C7H5ClO2
Molecular Weight	156.57 g/mol
Synonyms	3-Hydroxy-2-chlorobenzaldehyde; 2-Chloro-3-hydroxybenzaldehyde; 2-Chlorosalicylaldehyde; 2-Chloro-3-formylphenol; o-Chloro-m-hydroxybenzaldehyde; Salicylaldehyde, 2-chloro-; Benzaldehyde, 2-chloro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxybenzaldehyde is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure a typical purity of ≥97% and conformity to agreed specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.