Description

4-Oxo-4-(3-Trifluoromethylphenyl)Butyric Acid is a high-value aromatic keto acid derivative featuring a trifluoromethyl substituent, a functional group of significant interest in modern synthetic chemistry. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for the synthesis of more complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its unique trifluoromethylphenyl moiety into target structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and exploring new reaction pathways in academic and industrial laboratories.
• Peptide Mimetic & Bio-conjugate Chemistry: The carboxylic acid and ketone functionalities allow for conjugation and the creation of novel peptide analogs or drug-linker systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	4-Oxo-4-(3-Trifluoromethylphenyl)Butyric Acid
CAS No.	56948-76-6
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	4-Oxo-4-[3-(trifluoromethyl)phenyl]butanoic acid; 3'-Trifluoromethylbenzoylpropionic Acid; 4-(3-Trifluoromethylphenyl)-4-oxobutanoic Acid; γ-Oxo-3-(trifluoromethyl)hydrocinnamic Acid; 4-Oxo-4-(m-trifluoromethylphenyl)butyric Acid; Butanoic acid, 4-oxo-4-[3-(trifluoromethyl)phenyl]-; 56948-76-6; m-Trifluoromethyl-γ-oxobenzene butanoic acid
EINECS	Contact for details

Quality Control

Our 4-Oxo-4-(3-Trifluoromethylphenyl)Butyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.