Description

1-Dimethylamino-3-(Trimethylsilyl)-2-Propyne is a specialized organosilicon building block featuring both a silyl-protected alkyne and a tertiary amine functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials chemists for constructing novel compounds, including active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and silicon-containing advanced materials.
• Organic Synthesis Building Block: Employed in click chemistry (e.g., CuAAC reactions) and other coupling reactions to introduce both silyl and amino functionalities.
• Ligand Precursor: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Research & Development: A versatile reagent for academic and industrial R&D in medicinal and synthetic chemistry.

Basic Information

Product Name	1-Dimethylamino-3-(Trimethylsilyl)-2-Propyne
CAS No.	56849-88-8
Molecular Formula	C8H17NSi
Molecular Weight	155.31 g/mol
Synonyms	3-(Dimethylamino)-1-(trimethylsilyl)-1-propyne; N,N-Dimethyl-3-(trimethylsilyl)-2-propyn-1-amine; (3-Dimethylamino-1-propynyl)trimethylsilane; 1-Trimethylsilyl-3-dimethylaminopropyne; Propyne, 1-(dimethylamino)-3-(trimethylsilyl)-; DMATMS; (Dimethylamino)(trimethylsilyl)acetylene derivative
EINECS	Contact for details

Quality Control

Our 1-Dimethylamino-3-(Trimethylsilyl)-2-Propyne is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.