Description

Bis[(1β,5β)-8-Azabicyclo[3.2.1]Octan-3α-Yl]Methanone is a high-purity, specialized organic compound belonging to the class of nortropane derivatives. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold or building block for the design and synthesis of new chemical libraries in drug discovery programs.
• Alkaloid Synthesis: Serves as an intermediate in the synthesis of tropane and nortropane alkaloid analogs for biological evaluation.
• Ligand Development: Employed in the creation of specialized ligands for biochemical assays and receptor studies.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing of high-value, complex organic molecules.

Basic Information

Product Name	Bis[(1β,5β)-8-Azabicyclo[3.2.1]Octan-3α-Yl]Methanone
CAS No.	56847-09-7
Molecular Formula	C15H22N2O
Molecular Weight	246.35 g/mol
Synonyms	3α-Tropanoyl-3α-tropine; Bis(3α-tropanyl) ketone; 3α,3'α-Bitropanone; 3α-Tropan-3α-yl Tropan-3α-yl Ketone; NSC 169865; 3α-Tropoyl-3α-tropine; 3α,3'α-Ditropanone; 3α-Tropanyl 3α-Tropanoyl Ketone
EINECS	Contact for details

Quality Control

Our Bis[(1β,5β)-8-Azabicyclo[3.2.1]Octan-3α-Yl]Methanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.