Description

2,4-Bis[(Trimethylsilyl)Oxy]-5-Pyrimidinecarboxylic Acid Trimethylsilyl Ester is a highly functionalized, silyl-protected pyrimidine derivative. This compound serves as a versatile and reactive synthetic intermediate, particularly valuable for constructing complex nucleoside analogs and other heterocyclic systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral, anticancer, and other therapeutic nucleoside analogs.
• Agrochemical Research: Used in the development of new pesticides and herbicides that target specific biological pathways.
• Chemical Synthesis: Acts as a protected precursor for introducing the 5-carboxylic acid functionality of uracil and related pyrimidine bases under mild conditions.
• Material Science: Potential monomer or modifier in the creation of specialty polymers with tailored electronic or biological properties.
• Process Chemistry: Enables scalable, efficient routes to complex molecules due to its stability and reactivity profile.

Basic Information

Product Name	2,4-Bis[(Trimethylsilyl)Oxy]-5-Pyrimidinecarboxylic Acid Trimethylsilyl Ester
CAS No.	56804-96-7
Molecular Formula	C15H30N2O4Si3
Molecular Weight	386.66 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2,4-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester; Trimethylsilyl 2,4-bis(trimethylsiloxy)pyrimidine-5-carboxylate; 2,4-Bis(trimethylsiloxy)pyrimidine-5-carboxylic acid trimethylsilyl ester; Uracil-5-carboxylic acid tris(trimethylsilyl) ester; 5-(Trimethylsilyloxycarbonyl)-2,4-bis(trimethylsiloxy)pyrimidine; Tris-O-trimethylsilyl isoorotate
EINECS	Contact for details

Quality Control

Every batch of 2,4-Bis[(Trimethylsilyl)Oxy]-5-Pyrimidinecarboxylic Acid Trimethylsilyl Ester is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and consistency for your critical research and development applications. A detailed Certificate of Analysis (COA) including assay (HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition upon prolonged exposure to air. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.