Description

n-(1-Methylethyl)-L-Isoleucine 1-Methylethyl Ester is a specialized, optically active amino acid derivative with a protected ester group. This compound is a critical chiral building block in the synthesis of complex peptides and pharmaceutical intermediates, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, protease inhibitors, and other bioactive molecules.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce the L-isoleucine moiety with a protected side chain.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions due to its defined stereocenter.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Bioconjugation & Labeling: Potential use in modifying proteins or creating labeled compounds for diagnostic applications.
• Academic & R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	n-(1-Methylethyl)-L-Isoleucine 1-Methylethyl Ester
CAS No.	56771-55-2
Molecular Formula	C12H25NO2
Molecular Weight	215.33 g/mol
Synonyms	L-Isoleucine, N-(1-methylethyl)-, 1-methylethyl ester; Isopropyl L-isoleucinate N-isopropyl derivative; N-Isopropyl-L-isoleucine isopropyl ester; (2S,3S)-2-[(Propan-2-yl)amino]-3-methylpentanoic acid propan-2-yl ester; L-Isoleucine N-isopropyl isopropyl ester; N-Isopropylisoleucine isopropyl ester; Protected L-Isoleucine derivative
EINECS	Contact for details

Quality Control

Our n-(1-Methylethyl)-L-Isoleucine 1-Methylethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.