Description

3,7-Dihydro-1,3-Dimethyl-1H-Purine-2,6-Dione, Calcium Salt is a specialized pharmaceutical intermediate and fine chemical, recognized for its role as the calcium salt of the xanthine derivative theophylline. This compound is valued for its enhanced stability and solubility profile compared to its free acid form, making it a critical component in controlled-release and specialized drug formulations. It is primarily utilized by manufacturers in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and in advanced research and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of theophylline-based active pharmaceutical ingredients (APIs) and their derivatives.
• Respiratory Therapeutics: Used in the development of bronchodilator medications for treating conditions such as asthma and chronic obstructive pulmonary disease (COPD).
• Controlled-Release Formulations: Serves as a precursor for creating modified-release drug delivery systems due to its salt properties.
• Analytical Reference Standard: Employed as a high-purity standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Utilized in life science research to study adenosine receptor antagonism and related physiological pathways.
• Veterinary Pharmaceuticals: Applied in the formulation of certain veterinary medicines.

Basic Information

Product Name	3,7-Dihydro-1,3-Dimethyl-1H-Purine-2,6-Dione, Calcium Salt
CAS No.	56770-95-7
Molecular Formula	C14H18CaN8O4
Molecular Weight	426.43 g/mol
Synonyms	Calcium Theophylline; Theophylline Calcium Salt; 1,3-Dimethylxanthine Calcium Salt; Theocalcin; Theophylline Calcium; Theo-Cal; Calcium 1,3-Dimethyl-2,6-dioxo-7H-purin-7-ide
EINECS	Contact for details

Quality Control

Our 3,7-Dihydro-1,3-Dimethyl-1H-Purine-2,6-Dione, Calcium Salt is manufactured under strict quality management systems. We offer material suitable for pharmaceutical intermediate applications, with quality control adhering to in-house specifications designed to meet the stringent requirements of our global customer base. Certificates of Analysis (COA) documenting purity, identity, and related substances are provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Calcium Content (Titration)	9.0% - 10.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.