Description

3'-Bromo-4'-Nitroacetophenone is a high-purity, versatile aromatic ketone building block used in advanced organic synthesis. Its unique halogenated and nitrated structure makes it a critical intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing bromo and nitro functional groups for further derivatization.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromo-nitroacetophenone scaffold provides specific biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in electronic displays.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and other colorants.
• Academic and R&D: A valuable reagent for methodological studies in cross-coupling reactions, nitro group reductions, and ring-forming transformations.

Basic Information

Product Name	3'-Bromo-4'-Nitroacetophenone
CAS No.	56759-33-2
Molecular Formula	C8H6BrNO3
Molecular Weight	244.04 g/mol
Synonyms	1-(3-Bromo-4-nitrophenyl)ethanone; 3-Bromo-4-nitroacetophenone; 1-Acetyl-3-bromo-4-nitrobenzene; 3'-Bromo-4'-nitroacetophenone; 3-Bromo-4'-nitroacetophenone; Ethanone, 1-(3-bromo-4-nitrophenyl)-; 4'-Nitro-3'-bromoacetophenone
EINECS	Contact for details

Quality Control

Every batch of 3'-Bromo-4'-Nitroacetophenone is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical protocols, including HPLC, GC, and NMR for identity and purity verification. Certificates of Analysis (COA) detailing all specification parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.