Description

2'-Nitro-3'-Bromoacetophenone is a versatile and highly functionalized aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of both nitro and bromo substituents on the acetophenone core, which allows for sequential and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular architectures for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs), particularly those requiring nitro- or bromo-aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its reactive sites enable the creation of targeted bioactive molecules.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to the activated bromo group.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized azo dyes and other colorants where the nitro group acts as an auxochrome or electron-withdrawing group.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2'-Nitro-3'-Bromoacetophenone
CAS No.	56759-31-0
Molecular Formula	C8H6BrNO3
Molecular Weight	244.04 g/mol
Synonyms	1-(3-Bromo-2-nitrophenyl)ethan-1-one; 3'-Bromo-2'-nitroacetophenone; 2-Nitro-3-bromoacetophenone; 3-Bromo-2-nitroacetophenone; Ethanone, 1-(3-bromo-2-nitrophenyl)-; α-Bromo-2-nitroacetophenone (ambiguous, verify structure); 2-Nitro-m-bromoacetophenone
EINECS	Contact for details

Quality Control

Every batch of 2'-Nitro-3'-Bromoacetophenone is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all commercial shipments upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.