Description

4-(3H-Diazirin-3-Yl)Pyridine is a specialized heterocyclic compound featuring a diazirine ring fused to a pyridine moiety. This unique structure makes it a valuable photoaffinity labeling reagent and a versatile building block in chemical biology and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for probing biomolecular interactions and developing novel therapeutic agents.

Application

• Photoaffinity Labeling (PAL): A critical reagent for covalent cross-linking in the study of protein-ligand interactions, receptor mapping, and target identification.
• Chemical Biology Probes: Used to synthesize probes for activity-based protein profiling (ABPP) and other functional proteomics applications.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, particularly those targeting enzyme active sites.
• Bioconjugation: Enables the site-specific labeling of biomolecules (proteins, nucleic acids) for diagnostic and imaging applications.
• Materials Science Research: Employed in the surface functionalization of materials and the development of smart polymeric systems via photochemical reactions.
• Agrochemical Research: Used in the design and study of novel pesticides and herbicides that act on specific biological targets.

Basic Information

Product Name	4-(3H-Diazirin-3-Yl)Pyridine
CAS No.	56752-30-8
Molecular Formula	C7H5N3
Molecular Weight	131.14 g/mol
Synonyms	3-(Pyridin-4-yl)-3H-diazirine; 4-(Diazirin-3-yl)pyridine; 4-Pyridinyldiaziridine; Diazirine, 3-(4-pyridinyl)-; 3-(4-Pyridyl)diazirine; 4-Diazirinylpyridine; Photoaffinity Labeling Reagent
EINECS	Contact for details

Quality Control

Our 4-(3H-Diazirin-3-Yl)Pyridine is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and decomposition. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.