Description

3-(3H-Diazirin-3-Yl)Pyridine is a specialized heterocyclic compound featuring a diazirine functional group, a key photolabile moiety used for photoaffinity labeling and crosslinking studies. This compound matters for researchers and developers in life sciences and materials chemistry who require precise, light-activated molecular probes. It is primarily needed by pharmaceutical R&D teams, chemical biology laboratories, and advanced materials scientists for applications in drug discovery, proteomics, and surface functionalization.

Application

• Photoaffinity Labeling (PAL): A critical reagent for identifying and studying protein-ligand interactions and binding sites through covalent crosslinking initiated by UV light.
• Chemical Biology Probes: Used to synthesize photoactivatable probes for mapping biological pathways and enzyme active sites in living systems.
• Proteomics Research: Enables the capture and identification of transient or weak protein complexes for mass spectrometric analysis.
• Surface Modification: Facilitates the light-directed immobilization of molecules onto polymers, chips, or nanoparticles for biosensor and microarray development.
• Drug Discovery: Employed in target identification and validation stages to elucidate the mechanisms of action of novel therapeutic candidates.
• Materials Science: Serves as a photo-crosslinker in the development of smart polymers and responsive materials with light-triggered properties.

Basic Information

Product Name	3-(3H-Diazirin-3-Yl)Pyridine
CAS No.	56752-26-2
Molecular Formula	C7H6N3
Molecular Weight	132.15 g/mol
Synonyms	3-(3H-Diazirin-3-yl)pyridine; 3-Pyridinyldiaziridine; 3-(Diazirin-3-yl)pyridine; Diazirinylpyridine; Photoactivatable pyridine derivative; 3-Pyridyl diazirine; Diazirine-pyridine conjugate; 3-(3H-Diazirin-3-yl)pyridine, Diazirine functionalized pyridine
EINECS	Contact for details

Quality Control

Our 3-(3H-Diazirin-3-Yl)Pyridine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling and aliquoting should be performed under subdued light or amber glass to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.