Description

De-Epoxy Rosamicin CAS NO 56689-42-0 is a key macrolide antibiotic intermediate, derived from the modification of rosamicin to enhance its stability and pharmacological profile. This compound is critical for pharmaceutical R&D and manufacturing, particularly in the synthesis of advanced antibiotic agents targeting resistant bacterial strains. It serves as a vital building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing next-generation anti-infective therapies.

Application

• Primary intermediate in the synthesis of novel macrolide antibiotic derivatives.
• Research and development of new antibacterial agents with improved efficacy against drug-resistant pathogens.
• Production of reference standards for analytical method development and quality control in pharmaceutical manufacturing.
• Key starting material (KSM) for the preparation of specialized antibiotic compounds in GMP environments.
• Use in biochemical studies to investigate the structure-activity relationships (SAR) of macrolide antibiotics.

Basic Information

Product Name	De-Epoxy Rosamicin
CAS No.	56689-42-0
Molecular Formula	C31H53NO8
Molecular Weight	567.76 g/mol
Synonyms	Rosamicin, 9-Deoxo-9a-aza-9a-homoerythromycin A; 23-(Dimethylamino)-1,2,3,4,6,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,1000-Octahydro-3,5,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70,72,74,76,78,80,82,84,86,88,90,92,94,96,98,1000H-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70,72,74,76,78,80,82,84,86,88,90,92,94,96,98,1000-cyclopenta[a]phenanthren-1-one; Antibiotic Sch 13430; Rosamicin A; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our De-Epoxy Rosamicin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive analytical data, including HPLC purity, identification by spectroscopic methods, and impurity profiling. Certificates of Analysis (COA) are available for every batch and can be supplied upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.