Description

Sodium Triacetoxyborohydride is a versatile and highly selective reducing agent, widely recognized for its stability and effectiveness in organic synthesis. Its primary value lies in its ability to perform reductive aminations under mild conditions, offering superior chemoselectivity compared to more aggressive reagents. This makes it an indispensable tool for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries. The compound, with CAS number 56553-60-7, is particularly valued for its handling characteristics and compatibility with a range of functional groups.

Application

• Reductive Amination: The premier application for the selective reduction of imines and enamines to corresponding amines, a critical step in API (Active Pharmaceutical Ingredient) synthesis.
• Pharmaceutical Intermediate Synthesis: Key reagent in the production of complex drug molecules, including various amines and N-heterocycles.
• Agrochemical Manufacturing: Used in the synthesis of herbicide and pesticide intermediates requiring selective amine formation.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where controlled reduction is necessary.
• Academic & Process Research: A staple reagent in laboratory-scale development and optimization of synthetic routes due to its reliability.
• Peptide Chemistry: Can be utilized for the modification of amino acids or the reduction of related functionalities in peptide synthesis.

Basic Information

Product Name	Sodium Triacetoxyborohydride
CAS No.	56553-60-7
Molecular Formula	C6H10BNaO6
Molecular Weight	211.94 g/mol
Synonyms	Sodium Triacetoxyhydroborate; STAB; Sodium Triacetoxyborohydride; Borate(1-), triacetoxyhydro-, sodium (1:1); Sodium Hydrogen Triacetoxyborate; NaBH(OAc)3; Sodium (Triacetoxy)borohydride; Acetic acid, hydroborate (1-) triacetate, sodium salt
EINECS	Contact for details

Quality Control

Our Sodium Triacetoxyborohydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and moisture content. Our quality system is designed to meet the rigorous standards expected in pharmaceutical R&D and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the material should be handled under a dry inert atmosphere (e.g., nitrogen or argon) and the container kept sealed to minimize exposure to moisture. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in THF, DMF, DCM; reacts with water and protic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.