Description

(S)-2,3-Dihydro-6-(2-Hydroxyethyl)-5-Hydroxymethyl-2,7-Dimethyl-1H-Inden-1-One is a high-purity chiral indanone derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and key chiral intermediate for the development of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex chiral architectures.
• Asymmetric Synthesis: Utilized as a chiral synthon or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) where its specific stereochemistry is essential.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, fragrances, and advanced materials requiring the indanone moiety.
• Academic Research: A valuable compound for methodological studies in organic chemistry, particularly those exploring new cyclization or functionalization strategies.

Basic Information

Product Name	(S)-2,3-Dihydro-6-(2-Hydroxyethyl)-5-Hydroxymethyl-2,7-Dimethyl-1H-Inden-1-One
CAS No.	56374-22-2
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	(S)-6-(2-Hydroxyethyl)-5-(hydroxymethyl)-2,7-dimethyl-2,3-dihydro-1H-inden-1-one; (S)-1-Indanone, 2,3-dihydro-6-(2-hydroxyethyl)-5-(hydroxymethyl)-2,7-dimethyl-; (S)-Form of the indanone derivative; Chiral Dihydroxyethyl Dimethyl Indanone; (S)-Configured Indanone Intermediate; (S)-5-Hydroxymethyl-6-(2-hydroxyethyl)-2,7-dimethylindan-1-one
EINECS	Contact for details

Quality Control

Our (S)-2,3-Dihydro-6-(2-Hydroxyethyl)-5-Hydroxymethyl-2,7-Dimethyl-1H-Inden-1-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible quality and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.