Description

(1R,3S,5S,8E,12S,13R)-12-Hydroxy-5,9,13-trimethyl-16-methylene-4,14-dioxatricyclo[11.3.2.03,5]octadec-8-en-15-one is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound is valued for its unique structural framework, which serves as a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new plant protection agents and bioactive molecules due to its complex terpenoid backbone.
• Fine Chemical Synthesis: Acts as a precursor for synthesizing specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in total synthesis and natural product chemistry.
• Reference Standard: Utilized as an analytical standard for quality control and identification in related manufacturing processes.

Basic Information

Product Name	(1R,3S,5S,8E,12S,13R)-12-Hydroxy-5,9,13-trimethyl-16-methylene-4,14-dioxatricyclo[11.3.2.03,5]octadec-8-en-15-one
CAS No.	56326-25-1
Molecular Formula	C20H28O4
Molecular Weight	332.44 g/mol
Synonyms	12-Hydroxy-5,9,13-trimethyl-16-methylene-4,14-dioxatricyclo[11.3.2.03,5]octadec-8-en-15-one; (1R,3S,5S,8E,12S,13R)-Isomer; CAS 56326-25-1; 4,14-Dioxatricyclo[11.3.2.03,5]octadec-8-ene-15-one, 12-hydroxy-5,9,13-trimethyl-16-methylene-, (1R,3S,5S,8E,12S,13R)-; Sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Our (1R,3S,5S,8E,12S,13R)-12-Hydroxy-5,9,13-trimethyl-16-methylene-4,14-dioxatricyclo[11.3.2.03,5]octadec-8-en-15-one is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.