Description

5-(Trifluoromethyl)-2-Furoic Acid, 97 is a high-purity, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its ability to introduce the metabolically stable and lipophilic trifluoromethyl group into target molecules, significantly altering their physicochemical properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Material Science Precursor: Acts as a monomer or functionalizing agent for creating fluorinated polymers, coatings, and liquid crystals with unique thermal, chemical, and optical properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry Studies: Used as a standard or reagent in academic and industrial research focused on the synthesis and behavior of fluoroorganic compounds.

Basic Information

Product Name	5-(Trifluoromethyl)-2-Furoic Acid, 97
CAS No.	56286-73-8
Molecular Formula	C6H3F3O3
Molecular Weight	180.08 g/mol
Synonyms	5-(Trifluoromethyl)furan-2-carboxylic Acid; 2-Furoic acid, 5-(trifluoromethyl)-; α,α,α-Trifluoro-5-furoic Acid; 5-Trifluoromethyl-2-furancarboxylic Acid; 5-(Trifluoromethyl)-2-furanoic Acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2-Furoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the specified 97% minimum assay. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.