Description

[1R-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane] is a high-purity, stereochemically defined spirocyclic oxirane derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its rigid, three-dimensional bicyclic framework and reactive epoxide functionality make it invaluable for constructing complex molecular architectures with precise stereochemical control. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its unique spiro structure for bioactivity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral scaffold in the development of asymmetric catalysts for stereoselective reactions.
• Fine Chemical Production: Serves as a building block for high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.
• Material Science: Potential monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	[1R-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane]
CAS No.	56246-58-3
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	(1R,2R,5R)-6,6-Dimethylspiro[bicyclo[3.1.1]heptane-2,2'-oxirane]; (-)-6,6-Dimethylspiro[bicyclo[3.1.1]heptane-2,2'-oxirane]; (1R,5R)-6,6-Dimethylspiro[bicyclo[3.1.1]heptane-2,2'-oxirane]; Spiro[2.4]heptane, 6,6-dimethyl-, (1R,5R)-rel-; Pinane oxide derivative; Chiral spiro epoxide; Bicyclo[3.1.1]heptane-2,2'-oxirane, 6,6-dimethyl-, (1R,2R,5R)-
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane] is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.