Description

2-O,3-O:4-O,6-o-Bis(Methylboranediyl)-1-o-Trimethylsilyl-α-D-Mannopyranose is a sophisticated, organosilicon-protected carbohydrate derivative featuring a unique bis(methylboranediyl) bridge. This compound is a critical advanced synthetic intermediate for constructing complex glycomimetics and nucleoside analogs. It is primarily utilized by pharmaceutical R&D and specialty chemical synthesis teams requiring precise control over sugar chemistry and stereochemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Glycobiology Research: Used in the study of carbohydrate-protein interactions and the development of glycomimetic drugs.
• Oligosaccharide Synthesis: Serves as a protected mannose donor in the automated or solution-phase synthesis of complex carbohydrates.
• Chemical Biology Probes: Enables the creation of tagged or modified sugars for metabolic labeling and imaging studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of carbohydrate-based active pharmaceutical ingredients (APIs).
• Material Science: Potential precursor for synthesizing functionalized surfaces or polymers with specific sugar recognition properties.

Basic Information

Product Name	2-O,3-O:4-O,6-o-Bis(Methylboranediyl)-1-o-Trimethylsilyl-α-D-Mannopyranose
CAS No.	56246-46-9
Molecular Formula	C13H27B2O5Si
Molecular Weight	328.07 g/mol
Synonyms	1-O-Trimethylsilyl-2,3:4,6-di-O-methylboranyl-α-D-mannopyranose; α-D-Mannopyranose, 2,3:4,6-bis-O-(methylboranediyl)-1-O-(trimethylsilyl)-; TMS-Protected Methylboronate Mannose; 1-O-TMS-2,3:4,6-di-O-methylboranediyl-α-D-mannose; Methylboronated TMS-Mannose Derivative; 56246-46-9; α-D-Mannopyranose, bis(methylboranediyl) TMS ether
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O:4-O,6-o-Bis(Methylboranediyl)-1-o-Trimethylsilyl-α-D-Mannopyranose is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive synthetic applications. Certificates of Analysis (COA) detailing specifications from NMR, HPLC, and other relevant techniques are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.