Description

3α,16α-Bis[(Trimethylsilyl)Oxy]-5β-Androstan-17-One is a high-purity, protected steroid derivative, primarily utilized as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of complex steroid-based molecules, enabling precise chemical modifications. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Chemistry: Serves as a protected intermediate in the scalable production of more complex steroid derivatives, ensuring reaction selectivity.
• Reference Standard: Employed as an analytical standard in quality control (QC) and method development for HPLC, GC-MS, or NMR analysis.
• Biochemical Research: Utilized in the development of enzyme inhibitors or probes for studying steroidogenic pathways.
• Fine Chemical Synthesis: A precursor for creating specialized steroid compounds used in various high-value chemical applications.

Basic Information

Product Name	3α,16α-Bis[(Trimethylsilyl)Oxy]-5β-Androstan-17-One
CAS No.	56210-91-4
Molecular Formula	C25H46O3Si2
Molecular Weight	450.81 g/mol
Synonyms	5β-Androstan-17-one, 3α,16α-bis[(trimethylsilyl)oxy]-; 3α,16α-Bis(trimethylsiloxy)-5β-androstan-17-one; 3α,16α-Di-O-trimethylsilyl-5β-androstan-17-one; 5β-Androstane-3α,16α-diol 17-one bis(trimethylsilyl) ether; Androstane-17-one TMS derivative; 56210-91-4; 3α,16α-Bis(trimethylsilyloxy)-5β-androstan-17-one
EINECS	Contact for details

Quality Control

Every batch of 3α,16α-Bis[(Trimethylsilyl)Oxy]-5β-Androstan-17-One is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.