Description

(3R,3Ar,4R,6E,9R,10E,11Ar)-4,9-Bisacetoxy-3A,4,5,8,9,11A-Hexahydro-3,6,10-Trimethylcyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity chemical intermediate is valued for its unique stereochemistry and functional groups, which make it a critical building block in advanced synthetic organic chemistry. It is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel therapeutic agents and for use in pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Natural Product Synthesis: Acts as a sophisticated intermediate in the total or semi-synthesis of complex natural products and their analogs for biological evaluation.
• Biochemical Probe Development: Utilized in the design and creation of specific molecular probes to study biological pathways and enzyme interactions.
• High-Value Fine Chemical Production: Employed in the manufacture of specialty chemicals where precise stereochemical control is paramount.

Basic Information

Product Name	(3R,3Ar,4R,6E,9R,10E,11Ar)-4,9-Bisacetoxy-3A,4,5,8,9,11A-Hexahydro-3,6,10-Trimethylcyclodeca[B]Furan-2(3H)-One
CAS No.	56192-71-3
Molecular Formula	C19H26O6
Molecular Weight	350.41 g/mol
Synonyms	4,9-Bisacetoxy-3A,4,5,8,9,11A-hexahydro-3,6,10-trimethylcyclodeca[B]furan-2(3H)-one; 4,9-Diacetoxy-3A,4,5,8,9,11A-hexahydro-3,6,10-trimethylcyclodeca[B]furan-2(3H)-one; A sesquiterpene lactone diacetate; Cyclodeca[B]furan-2(3H)-one derivative; (3R,3aR,4R,6E,9R,10E,11aR)-4,9-Bis(acetyloxy)-3a,4,5,8,9,11a-hexahydro-3,6,10-trimethyl-; 56192-71-3 (CAS name basis)
EINECS	Contact for details

Quality Control

Our (3R,3Ar,4R,6E,9R,10E,11Ar)-4,9-Bisacetoxy-3A,4,5,8,9,11A-Hexahydro-3,6,10-Trimethylcyclodeca[B]Furan-2(3H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at -20°C to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.