Description

2H-Oxecin-2-One, 3,4,7,8,9,10-Hexahydro-4-Hydroxy-10-Methyl-, [4S-(4R* ,5E,10S*)]- is a high-purity, stereochemically defined lactone compound of significant interest in advanced organic synthesis. This molecule serves as a critical chiral building block and intermediate for the development of complex natural products and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex macrolide and polyketide-based drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in stereoselective chemical reactions to construct complex molecular architectures.
• Natural Product Synthesis: Serves as a core structural unit in the laboratory synthesis of natural products containing medium-ring lactone motifs.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities (NCEs) for biological screening and lead compound development.
• Fine Chemical Production: Used in the manufacture of high-value, low-volume specialty chemicals for advanced material science and agrochemical applications.
• Academic Research: A valuable compound for methodological studies in organic chemistry, particularly in ring-closing metathesis and lactonization reactions.

Basic Information

Product Name	2H-Oxecin-2-One, 3,4,7,8,9,10-Hexahydro-4-Hydroxy-10-Methyl-, [4S-(4R* ,5E,10S*)]-
CAS No.	56020-71-4
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; 4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; 10-Methyl-4-hydroxy-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; (4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; (4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; (4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; (4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one; (4S,5E,10S)-4-Hydroxy-10-methyl-3,4,7,8,9,10-hexahydro-2H-oxecin-2-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Our quality management system supports the production of materials suitable for use under cGMP guidelines for non-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.