Description

2-Chloro-3-Methyl-1-[4-(1-Methylethyl)Phenyl]-1-Butanone is a specialized aromatic ketone derivative with a unique halogenated structure, serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of fine chemicals and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral and steric properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring a substituted phenylbutanone core structure.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its chlorinated moiety can impart specific biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance compounds, dyes, and other high-value specialty chemicals.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and carbonyl chemistry explorations.
• Material Science Research: Investigated as a monomer or cross-linking agent precursor for the development of novel polymeric materials with specific thermal or optical properties.

Basic Information

Product Name	2-Chloro-3-Methyl-1-[4-(1-Methylethyl)Phenyl]-1-Butanone
CAS No.	55955-90-3
Molecular Formula	C14H17ClO
Molecular Weight	236.74 g/mol
Synonyms	2-Chloro-3-methyl-1-(4-isopropylphenyl)butan-1-one; 1-(4-Isopropylphenyl)-2-chloro-3-methyl-1-butanone; α-Chloro-β-methyl-4-isopropylpropiophenone; 4'-Isopropyl-2-chloro-3-methylbutyrophenone; 55955-90-3; Butanone, 2-chloro-3-methyl-1-[4-(1-methylethyl)phenyl]-; p-Isopropyl-α-chloro-β-methylpropiophenone
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Methyl-1-[4-(1-Methylethyl)Phenyl]-1-Butanone undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and scale-up applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay purity (by HPLC/GC), identity confirmation (by IR, NMR), and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.