Description

1-Bromo-2-Chlorocyclobutane is a versatile halogenated cyclobutane derivative, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring both bromine and chlorine substituents on a strained four-membered ring, makes it a valuable precursor for constructing complex molecular architectures and functional materials. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce the cyclobutyl moiety or to undergo further selective functionalization.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting cyclobutane-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can contribute to unique biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to create complex organic molecules for various R&D applications.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	1-Bromo-2-Chlorocyclobutane
CAS No.	55887-83-7
Molecular Formula	C4H6BrCl
Molecular Weight	169.45 g/mol
Synonyms	2-Chloro-1-bromocyclobutane; Cyclobutane, 1-bromo-2-chloro-; 1-Bromo-2-chloro-cyclobutane; Bromochlorocyclobutane; (1-Bromo-2-chlorocyclobutyl)radical; 1-Chloro-2-bromocyclobutane
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chlorocyclobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.6 g/cm³
Boiling Point	~65-70°C / 15 mmHg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.