Description

3α-Methoxy-16,16-Dimethyl-5α-Androstan-17-One is a high-purity synthetic steroid intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel steroidal drugs, enabling precise structural modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel steroidal active pharmaceutical ingredients (APIs) and investigational new drugs.
• Research & Development: Used in academic and industrial laboratories for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Hormone Analog Development: Serves as a scaffold for creating modified androgens and other hormone receptor modulators.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scaling up synthetic routes for potential commercial drug candidates.

Basic Information

Product Name	3α-Methoxy-16,16-Dimethyl-5α-Androstan-17-One
CAS No.	55836-75-4
Molecular Formula	C22H36O2
Molecular Weight	332.52 g/mol
Synonyms	3α-Methoxy-16,16-dimethyl-5α-androstan-17-one; 16,16-Dimethyl-3α-methoxy-5α-androstan-17-one; 3-Methoxy-16,16-dimethyl-5α-androstan-17-one; 5α-Androstan-17-one, 3-methoxy-16,16-dimethyl-; Androstane derivative 55836-75-4
EINECS	Contact for details

Quality Control

Our 3α-Methoxy-16,16-Dimethyl-5α-Androstan-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to store under an inert gas such as nitrogen or argon for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.