Description

2-Ethyl-3-Hydroxy-4-Phenylbutyric Acid is a versatile chiral intermediate with significant synthetic utility. Its molecular structure, featuring both hydroxyl and carboxylic acid functional groups on a phenyl-substituted carbon chain, makes it a valuable building block for the production of complex organic molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and drug development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Asymmetric Synthesis: Used as a starting material or resolving agent in the preparation of enantiomerically pure compounds.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other specialty organic compounds requiring specific stereochemistry.
• Research & Development: Employed in academic and industrial R&D for methodological studies in organic chemistry and catalysis.
• Agrochemical Synthesis: Potential intermediate in the development of chiral pesticides and herbicides.

Basic Information

Product Name	2-Ethyl-3-Hydroxy-4-Phenylbutyric Acid
CAS No.	55822-89-4
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	3-Hydroxy-2-ethyl-4-phenylbutanoic Acid; (3R/S)-3-Hydroxy-2-ethyl-4-phenylbutyric Acid; 2-Ethyl-3-hydroxy-4-phenylbutanoic Acid; (±)-2-Ethyl-3-hydroxy-4-phenylbutyric Acid; DL-2-Ethyl-3-hydroxy-4-phenylbutyric Acid; Ethylhydroxyphenylbutyric Acid; NSC 403714
EINECS	Contact for details

Quality Control

Our 2-Ethyl-3-Hydroxy-4-Phenylbutyric Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chromatographic purity assays and chiral analysis, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.