Description

Ethyl 2-Fluoroisobutyrate is a valuable fluorinated ester building block used in advanced organic synthesis. This compound is essential for introducing the 2-fluoro-2-methylpropanoate moiety, a key structural feature that can modulate the biological activity and metabolic stability of target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where the fluorine atom enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from fluorinated chemical structures for improved efficacy and environmental profile.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the α-fluorinated isobutyrate group in complex molecule construction, including natural product analogs and specialty chemicals.
• Material Science Precursor: Employed in the development of fluorinated polymers and specialty materials with unique surface properties, chemical resistance, or optical characteristics.
• Fluorine Chemistry Research: A critical compound for academic and industrial research exploring new methodologies in fluorination and the development of novel fluorinated compounds.

Basic Information

Product Name	Ethyl 2-Fluoroisobutyrate
CAS No.	55816-69-8
Molecular Formula	C6H11FO2
Molecular Weight	134.15 g/mol
Synonyms	Ethyl 2-Fluoro-2-methylpropanoate; 2-Fluoro-2-methylpropanoic Acid Ethyl Ester; Ethyl α-Fluoroisobutyrate; 2-Fluoroisobutyric Acid Ethyl Ester; Ethyl 2-Fluoro-2-methylpropionate; 55816-69-8; Ethyl 2-fluoro-2-methylpropanoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoroisobutyrate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.