Description

4Aα,9β-Dihydroxy-1β-Methyl-8-Methylenegibbane-1α,10β-Dicarboxylic Acid 1,4A-Lactone is a high-purity gibbane-type diterpenoid lactone derivative, valued for its complex stereochemistry and functional groups which make it a critical intermediate in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where it serves as a sophisticated building block for novel active ingredients. It is primarily sought by R&D chemists and process development scientists working on complex natural product analogs, plant growth regulators, and specialized fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in oncology and metabolic disease research.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced plant growth regulators and environmentally benign pesticides.
• Natural Product Synthesis: Used in academic and industrial laboratories for the total synthesis or structural modification of complex diterpenoid natural products.
• Biochemical Research: Employed as a standard or probe in studies investigating plant hormone pathways and biosynthetic mechanisms.
• Fine Chemical Manufacturing: Acts as a high-value intermediate for custom synthesis and contract manufacturing organizations (CMOs) serving the life sciences industry.

Basic Information

Product Name	4Aα,9β-Dihydroxy-1β-Methyl-8-Methylenegibbane-1α,10β-Dicarboxylic Acid 1,4A-Lactone
CAS No.	55812-47-0
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	Gibberellin A4 Lactone; GA4 Lactone; 1α,10β-Dicarboxy-8-methylenegibbane-4aα,9β-diol 1,4a-lactone; 8-Methylenegibbane-1α,10β-dicarboxylic acid, 4aα,9β-dihydroxy-, 1,4a-lactone; (1α,4aα,9β,10β)-4a,9-Dihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone; Gibbane-1α,10β-dicarboxylic acid, 4aα,9β-dihydroxy-1β-methyl-8-methylene-, 1,4a-lactone
EINECS	Contact for details

Quality Control

Every batch of 4Aα,9β-Dihydroxy-1β-Methyl-8-Methylenegibbane-1α,10β-Dicarboxylic Acid 1,4A-Lactone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and MS is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.