Description

4'-Iodo-2-Phenylacetophenone is a high-purity iodinated aromatic ketone, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a phenylacetophenone backbone and an iodine substituent, makes it an essential precursor for constructing complex molecules, particularly in pharmaceutical research and material science. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the iodine atom facilitates further functionalization.
• Ligand & Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive materials due to its conjugated system and heavy atom effect.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including Suzuki-Miyaura and other palladium-catalyzed cross-couplings.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4'-Iodo-2-Phenylacetophenone
CAS No.	55794-28-0
Molecular Formula	C14H11IO
Molecular Weight	322.14 g/mol
Synonyms	2-Phenyl-4'-iodoacetophenone; 4'-Iodo-2-phenacylbenzene; 1-(4-Iodophenyl)-2-phenylethan-1-one; (4-Iodophenyl)(phenyl)methanone; 4-Iodobenzyl Phenyl Ketone; p-Iodophenyl Phenyl Ketone; α-Oxo-4-iodobenzeneacetonitrile (related); CAS 55794-28-0
EINECS	Contact for details

Quality Control

Our 4'-Iodo-2-Phenylacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assay and identity confirmation by IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications, and our quality systems are designed to meet the stringent requirements of global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent contamination and moisture absorption. Store away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.