Description

1-(2,5-Difluorophenyl)Butan-1-One is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require a difluorophenyl moiety.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the difluorophenyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways in fluorine chemistry.
• Specialty Polymer Modifier: Can be incorporated as a monomer or additive to impart specific properties like chemical resistance or altered refractive index in high-performance polymers.

Basic Information

Product Name	1-(2,5-Difluorophenyl)Butan-1-One
CAS No.	55787-96-7
Molecular Formula	C₁₀H₁₀F₂O
Molecular Weight	184.18 g/mol
Synonyms	1-Butanone, 1-(2,5-difluorophenyl)-; 2',5'-Difluorobutyrophenone; 1-(2,5-Difluorophenyl)-1-butanone; Butyrophenone, 2',5'-difluoro-; 2,5-Difluorobutyrophenone; 4-Fluoro-α-ethyl-2-fluorobenzyl alcohol (tautomer); DFBP
EINECS	Contact for details

Quality Control

Our production of 1-(2,5-Difluorophenyl)Butan-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.