Description

Ethyl 2-(3-n-Phthalimidopropyl)Acetoacetate is a specialized organic compound featuring a phthalimide-protected amine and an acetoacetate ester functional group. This unique bifunctional structure makes it a valuable high-purity building block for the synthesis of complex molecules. It is primarily utilized by pharmaceutical and advanced fine chemical research and development teams requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a protected amine linkage.
• Peptidomimetic Research: Serves as a crucial building block for creating peptide analogs and mimetics in drug discovery programs.
• Linker Chemistry: Used in the development of chemical linkers for bioconjugation and prodrug strategies.
• Advanced Organic Synthesis: Employed in multi-step synthetic routes to construct complex heterocycles and functionalized target molecules.
• Chemical Biology Probes: Acts as a starting material for synthesizing labeled compounds and molecular probes for biological studies.

Basic Information

Product Name	Ethyl 2-(3-n-Phthalimidopropyl)Acetoacetate
CAS No.	55747-45-0
Molecular Formula	C₁₇H₁₉NO₅
Molecular Weight	317.34 g/mol
Synonyms	Ethyl 2-(3-Phthalimidopropyl)Acetoacetate; Ethyl 3-(3-Phthalimidopropyl)-3-oxopropanoate; 2-(3-Phthalimidopropyl)Acetoacetic Acid Ethyl Ester; Acetoacetic Acid, 2-(3-Phthalimidopropyl)-, Ethyl Ester; 3-Oxo-3-(3-phthalimidopropyl)butanoic Acid Ethyl Ester; Ethyl 3-Oxo-5-phthalimidopentanoate; N-(3-Carbethoxy-3-oxopropyl)phthalimide (related structure)
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-n-Phthalimidopropyl)Acetoacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.