Description

4-tert-Butyl-3-Hydroxy-2,6-Dimethylphenylacetonitrile is a specialized organic intermediate featuring a sterically hindered phenolic structure combined with a nitrile functional group. This unique molecular architecture makes it a valuable building block for the synthesis of high-performance antioxidants, UV stabilizers, and specialty polymers. It is primarily sought after by R&D chemists and production specialists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced stability and functionality.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring hindered phenol motifs for antioxidant activity.
• Polymer Additive Synthesis: Used to manufacture high-efficiency phenolic antioxidants and light stabilizers for plastics, rubber, and synthetic fibers to prevent thermal and oxidative degradation.
• Agrochemical Development: Acts as a crucial building block for creating new-generation pesticides and herbicides, where its structural features can contribute to product stability and efficacy.
• Fine Chemical Synthesis: Employed in organic synthesis for constructing complex molecules in research and industrial-scale production of dyes, pigments, and other performance chemicals.
• Liquid Crystal & Electronic Materials: Potential intermediate in the production of advanced materials for electronic displays and organic semiconductors due to its rigid, substituted aromatic core.

Basic Information

Product Name	4-tert-Butyl-3-Hydroxy-2,6-Dimethylphenylacetonitrile
CAS No.	55699-10-0
Molecular Formula	C₁₄H₁₉NO
Molecular Weight	217.31 g/mol
Synonyms	2-(3-Hydroxy-2,6-dimethyl-4-tert-butylphenyl)acetonitrile; 4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl cyanide; 3-Hydroxy-2,6-dimethyl-4-tert-butylbenzyl cyanide; Benzenepropanenitrile, β-hydroxy-α,α,4-trimethyl-; (3-Hydroxy-2,6-dimethyl-4-tert-butylphenyl)acetonitrile; 4-(1,1-Dimethylethyl)-3-hydroxy-2,6-dimethylbenzenepropanenitrile
EINECS	Contact for details

Quality Control

Our production of 4-tert-Butyl-3-Hydroxy-2,6-Dimethylphenylacetonitrile adheres to stringent in-process and final release controls to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. Due to the phenolic hydroxy group, the material may be sensitive to prolonged exposure to air and moisture; store under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.