Description

(1R,5S,6S)-3-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid CAS NO 55685-58-0 is a high-purity, chiral bicyclic compound that serves as a critical advanced pharmaceutical intermediate and versatile synthetic building block. Its unique constrained oxabicyclo[3.1.0]hexane scaffold is highly valued for introducing structural complexity and specific stereochemistry into target molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Utilized as a building block for constructing complex, stereochemically defined molecular architectures in medicinal chemistry and total synthesis projects.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Protease Inhibitor Research: The carboxylic acid functionality and rigid bicyclic core make it a valuable scaffold for designing enzyme inhibitors.
• Material Science: Potential monomer or precursor for specialized polymers with unique thermal or mechanical properties derived from its strained ring system.
• Agrochemical Synthesis: Intermediate in the development of new, high-performance crop protection agents with specific modes of action.

Basic Information

Product Name	(1R,5S,6S)-3-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid
CAS No.	55685-58-0
Molecular Formula	C7H8O3
Molecular Weight	140.14 g/mol
Synonyms	(1R,5S,6S)-3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid; (1R,5S,6S)-6-Carboxy-3-oxabicyclo[3.1.0]hexane; (-)-3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid; (1R,5S,6S)-OBCA; 3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid, (1R,5S,6S)-; Bicyclo[3.1.0]hexane-6-carboxylic acid, 3-oxa-, (1R,5S,6S)-
EINECS	Contact for details

Quality Control

Our (1R,5S,6S)-3-Oxabicyclo[3.1.0]Hexane-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.