Description

2-Methyl-3-[2-[[(Trimethylsilyl)Oxy]Methyl]Phenyl]Quinazolin-4(3H)-One is a specialized quinazolinone derivative featuring a trimethylsilyl-protected hydroxymethyl group, making it a valuable synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for use as a key building block in active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those with quinazolinone-based pharmacophores.
• Organic Synthesis Reagent: Used in advanced organic reactions where its protected functional group allows for selective transformations under specific conditions.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging the biological activity of the quinazolinone core.
• Material Science Precursor: Acts as a starting material for the synthesis of specialty chemicals and functional materials.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for method development and exploratory chemistry projects.

Basic Information

Product Name	2-Methyl-3-[2-[[(Trimethylsilyl)Oxy]Methyl]Phenyl]Quinazolin-4(3H)-One
CAS No.	55683-29-9
Molecular Formula	C20H24N2O2Si
Molecular Weight	352.51 g/mol
Synonyms	2-Methyl-3-[2-[(trimethylsilyloxy)methyl]phenyl]-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-methyl-3-[2-[[(trimethylsilyl)oxy]methyl]phenyl]-; 2-Methyl-3-(2-((trimethylsilyloxy)methyl)phenyl)quinazolin-4(3H)-one; TMS-protected Quinazolinone Derivative; CAS 55683-29-9
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-[2-[[(Trimethylsilyl)Oxy]Methyl]Phenyl]Quinazolin-4(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades, from research (95%+) to high-purity (98%+) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.