Description

2-(Trimethylsiloxy)Pentanedioic Acid Dimethyl Ester is a specialized organosilicon compound that serves as a valuable synthetic intermediate and protecting group reagent. Its core value lies in its ability to introduce silyl-protected functionalities, enabling complex multi-step organic syntheses with high selectivity and yield. This chemical is particularly needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected carboxylic acid or hydroxyl groups.
• Peptide Synthesis: Used as a protecting group reagent for carboxylic acids during solid-phase and solution-phase peptide synthesis.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in various carbon-carbon bond forming reactions and as a precursor to other functionalized silanes.
• Polymer Modification: Used to introduce silyl groups into polymer backbones, altering properties like solubility, thermal stability, and surface characteristics.
• Material Science Research: Serves as a precursor for silicon-containing hybrid materials and surface coatings.

Basic Information

Product Name	2-(Trimethylsiloxy)Pentanedioic Acid Dimethyl Ester
CAS No.	55590-88-0
Molecular Formula	C10H20O5Si
Molecular Weight	248.35 g/mol
Synonyms	Dimethyl 2-(trimethylsiloxy)pentanedioate; 2-(Trimethylsilyloxy)glutaric Acid Dimethyl Ester; Glutaric Acid, 2-(Trimethylsiloxy)-, Dimethyl Ester; 2-(Trimethylsiloxy)glutaric Acid Dimethyl Ester; (Trimethylsiloxy)glutaric Acid Dimethyl Ester; TMS-protected Glutarate Ester; CAS 55590-88-0
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsiloxy)Pentanedioic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions, such as a nitrogen atmosphere, to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.05 - 1.10
Refractive Index (n20D)	1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.