Description

2-[(Trimethylsilyloxy)Methyl]-5-(Trimethylsilyloxy)-4H-Pyran-4-One is a specialized organosilicon-protected derivative of a pyranone core, serving as a key synthetic intermediate. Its primary value lies in its role as a protected precursor for the synthesis of complex natural products and active pharmaceutical ingredients (APIs), offering enhanced stability and solubility for advanced organic transformations. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in antibiotic and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the protected hydroxyl groups enable selective reactions.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry, including new coupling and cyclization reactions.
• Material Science: Potential monomer or modifier in the development of silicon-containing polymers with specific optical or electronic properties.

Basic Information

Product Name	2-[(Trimethylsilyloxy)Methyl]-5-(Trimethylsilyloxy)-4H-Pyran-4-One
CAS No.	55557-21-6
Molecular Formula	C13H26O4Si2
Molecular Weight	302.52 g/mol
Synonyms	4H-Pyran-4-one, 2-[(trimethylsilyloxy)methyl]-5-(trimethylsilyloxy)-; 2,5-Bis(trimethylsilyloxy)methyl-4H-pyran-4-one; 2,5-Bis-O-(trimethylsilyl)kojic acid; Kojic acid bis(trimethylsilyl) ether; Kojic acid bis-TMS ether; TMS-protected kojic acid derivative; 55557-21-6; 2,5-Bis(trimethylsiloxy)methyl-4-pyranone
EINECS	Contact for details

Quality Control

Our 2-[(Trimethylsilyloxy)Methyl]-5-(Trimethylsilyloxy)-4H-Pyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.