Description

(1S)-1,2,3,4,4A,5,6,7,8,8Aβ-Decahydro-1α,4Aβ-Dimethyl-6-Methylene-5β-[(3S)-3-Methyl-5-Oxohexyl]-1β-Naphthalenecarboxylic Acid Methyl Ester is a high-purity, complex diterpenoid ester of significant interest in advanced organic synthesis. This compound serves as a critical chiral intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and chemical manufacturers engaged in the synthesis of steroid analogs, terpenoid derivatives, and other complex natural product-inspired compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new therapeutic agents, particularly in steroid and terpenoid-based drug discovery.
• Organic Synthesis: Used as a sophisticated starting material or intermediate for constructing complex polycyclic frameworks in academic and industrial laboratories.
• Natural Product Synthesis: Essential for the semi-synthesis or total synthesis of complex natural products with diterpenoid skeletons.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of bioactive terpenoids and their derivatives.
• Fine Chemical Production: Serves as a precursor in the manufacture of high-value specialty chemicals for advanced material science and catalysis.

Basic Information

Product Name	(1S)-1,2,3,4,4A,5,6,7,8,8Aβ-Decahydro-1α,4Aβ-Dimethyl-6-Methylene-5β-[(3S)-3-Methyl-5-Oxohexyl]-1β-Naphthalenecarboxylic Acid Methyl Ester
CAS No.	55515-21-4
Molecular Formula	C25H38O3
Molecular Weight	386.57 g/mol
Synonyms	Methyl (1S,4aS,5S,8aR)-5-[(3S)-3-Methyl-5-oxohexyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylate; 6-Methyleneandrosta-1,4-diene-3,17-dione derivative; Diterpenoid Methyl Ester; 5β-[(3S)-3-Methyl-5-oxohexyl]-1β,4aβ-dimethyl-6-methylenedecahydronaphthalene-1α-carboxylic Acid Methyl Ester; Labdane Diterpenoid Intermediate; CAS 55515-21-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for pharmaceutical-grade intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to prolonged exposure to heat, moisture, and strong oxidizing agents. Keep the container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.