Description

2,4-Dimethylphenylboronic Acid is a versatile organoboron compound widely utilized as a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted biphenyl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for optimal bioactivity.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis and other boronic acid-based catalysts.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronic acid's affinity for diols, such as sugars.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories engaged in novel organic molecule discovery.

Basic Information

Product Name	2,4-Dimethylphenylboronic Acid
CAS No.	55499-44-0
Molecular Formula	C8H11BO2
Molecular Weight	149.98 g/mol
Synonyms	(2,4-Dimethylphenyl)boronic acid; 2,4-Dimethylbenzeneboronic acid; 2,4-Xylylboronic acid; B-(2,4-Dimethylphenyl)boronic acid; 2,4-Dimethylphenylboronic acid; Boronic acid, B-(2,4-dimethylphenyl)-; (2,4-Dimethylphenyl)boronic acid (contains varying amounts of anhydride)
EINECS	Contact for details

Quality Control

Our 2,4-Dimethylphenylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.