Description

Phosphoric Acid, 2-(Ethoxyimino)-3-[(Trimethylsilyl)Oxy]Propyl Bis(Tri Methylsilyl) Ester, (Z)- is a specialized organosilicon-protected phosphoric acid derivative, primarily used as a key synthetic intermediate. Its value lies in its role as a protected phosphate group donor, enabling complex organic synthesis under mild conditions while preventing unwanted side reactions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in nucleotide and phospholipid chemistry.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of nucleotide analogs, prodrugs, and other bioactive phosphate-containing molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators requiring phosphate ester functionalities.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for introducing protected phosphate groups.
• Material Science: Potential precursor for surface-modifying agents or specialty polymers with silicon-phosphate backbones.
• Process Chemistry: Enables efficient, scalable manufacturing routes for complex organic phosphates in GMP environments.

Basic Information

Product Name	Phosphoric Acid, 2-(Ethoxyimino)-3-[(Trimethylsilyl)Oxy]Propyl Bis(Tri Methylsilyl) Ester, (Z)-
CAS No.	55334-94-6
Molecular Formula	C17H44NO6PSi4
Molecular Weight	518.94 g/mol
Synonyms	(Z)-2-(Ethoxyimino)-3-[(trimethylsilyl)oxy]propyl bis(trimethylsilyl) phosphate; Phosphoric Acid Tris(trimethylsilyl) Ester Derivative; O-Protected Phosphorylating Agent; TMS-Protected Phosphoric Acid Ester; 55334-94-6; (Z)-Isomer of Phosphoric Acid Silyl Ester; [2-(Ethoxyimino)-3-(trimethylsilyloxy)propyl] Bis(trimethylsilyl) Phosphate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, isomeric purity (Z-configuration), and potency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Z-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.