Description

(18α)-5-Methyl-11-Oxo-25-Noroleana-9,12-Dien-29-Oic Acid is a high-purity, semi-synthetic triterpenoid derivative of oleanolic acid, valued for its role as a critical intermediate in advanced pharmaceutical research and synthesis. This compound is essential for medicinal chemistry programs focused on developing novel therapeutic agents, particularly in the fields of oncology and metabolic disease. Research and development laboratories, as well as fine chemical manufacturers serving the pharmaceutical industry, rely on this high-quality intermediate for its structural specificity and synthetic utility.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel triterpenoid-based drug candidates with potential anti-inflammatory, anti-cancer, or hepatoprotective activities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological profile of oleanane-type triterpenoids.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing complex natural product derivatives.
• Biochemical Tool Compound: Employed in preclinical research to investigate specific biological pathways and molecular targets influenced by modified triterpenoids.
• Fine Chemical Synthesis: Utilized as a specialized starting material for the custom synthesis of more complex, targeted molecules for client-specific R&D projects.

Basic Information

Product Name	(18α)-5-Methyl-11-Oxo-25-Noroleana-9,12-Dien-29-Oic Acid
CAS No.	55282-47-8
Molecular Formula	C29H42O3
Molecular Weight	438.64 g/mol
Synonyms	25-Norolean-9,12-dien-29-oic acid, 18α-5-methyl-11-oxo-; 18α-5-Methyl-11-oxo-25-norolean-9,12-dien-29-oic acid; 11-Oxo-18α-5-methyl-25-norolean-9,12-dien-29-oic acid; Modified Oleanolic Acid Derivative; 25-Noroleana-9,12-dien-29-oic acid derivative; Triterpenoid intermediate 55282-47-8; 18α-H-5-Methyl-11-oxo-25-norolean-9,12-dien-29-oic acid
EINECS	Contact for details

Quality Control

Our (18α)-5-Methyl-11-Oxo-25-Noroleana-9,12-Dien-29-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.