Description

2-(1-Methylbutoxy)-1,3,2-Dioxaborinane is a specialized organoboron reagent, a cyclic boronic ester known for its utility as a protected boronic acid equivalent in advanced synthetic chemistry. This compound matters for its role in facilitating key carbon-carbon and carbon-heteroatom bond-forming reactions, particularly in cross-coupling and Suzuki-Miyaura reactions, where it offers enhanced stability and handling compared to its boronic acid counterparts. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).

Application

• Key intermediate in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl structures.
• Protected boronic acid source in multi-step organic synthesis, particularly for pharmaceutical intermediates.
• Reagent for polymer modification and the synthesis of functional materials.
• Building block in agrochemical research for developing novel active ingredients.
• Used in academic and industrial R&D for methodology development and library synthesis.
• Potential precursor for boron neutron capture therapy (BNCT) agent research.

Basic Information

Product Name	2-(1-Methylbutoxy)-1,3,2-Dioxaborinane
CAS No.	55162-69-1
Molecular Formula	C9H17BO3
Molecular Weight	184.04 g/mol
Synonyms	1,3,2-Dioxaborinane, 2-(1-methylbutoxy)-; 2-(1-Methylbutoxy)-1,3,2-dioxaborinane; 2-(sec-Pentyloxy)-1,3,2-dioxaborinane; 2-(1-Methylbutoxy)-1,3,2-dioxaborinane; 2-(sec-Amyloxy)-1,3,2-dioxaborinane; Cyclic sec-pentyl boronate; Boronic acid, (1-methylbutyl) ester, cyclic ester with 1,3-propanediol
EINECS	Contact for details

Quality Control

Our 2-(1-Methylbutoxy)-1,3,2-Dioxaborinane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All products undergo rigorous analytical testing, including NMR (¹H, ¹¹B, ¹³C), GC or HPLC for purity determination, and Karl Fischer titration for moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.