Description

2-[(2-Methylcyclohexyl)Oxy]-1,3,2-Dioxaborolane is a specialized organoboron reagent, a cyclic boronic ester known for its utility as a protected boronic acid equivalent. This compound is valued for its enhanced stability and handling properties compared to its free boronic acid counterpart, making it a crucial intermediate in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and functional material synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant precursor for generating aryl and vinyl boronic acids in situ for C-C bond formation.
• Pharmaceutical Intermediate Synthesis: Used in the construction of complex drug molecules and active pharmaceutical ingredients (APIs) requiring boron-containing motifs.
• Agrochemical Production: Employed in the synthesis of novel herbicides, fungicides, and insecticides that incorporate boron heterocycles.
• Materials Science & OLED Development: Acts as a key building block for creating organic semiconductors, luminescent materials, and electron-transport layers.
• Polymer Chemistry: Utilized as a monomer or modifying agent in the synthesis of boron-containing polymers with unique thermal or electronic properties.
• Chemical Research & Process Development: Provides a reliable and storable source of the 2-methylcyclohexyloxyboronate group for method development and scale-up studies.

Basic Information

Product Name	2-[(2-Methylcyclohexyl)Oxy]-1,3,2-Dioxaborolane
CAS No.	55162-66-8
Molecular Formula	C9H17BO3
Molecular Weight	184.04 g/mol
Synonyms	2-Methylcyclohexyl Boronic Acid, Cyclic Ester; 2-Methylcyclohexane-1,3,2-dioxaborolane (substituted); 2-(2-Methylcyclohexyloxy)-1,3,2-dioxaborolane; 2-Methylcyclohexyloxy-1,3,2-dioxaborolane; (2-Methylcyclohexyl) Boronic Acid, Cyclic Ester; 2-Methylcyclohexyl Boric Acid, Cyclic Ester; Pinacol (2-Methylcyclohexyl)boronate; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of 2-[(2-Methylcyclohexyl)Oxy]-1,3,2-Dioxaborolane adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. All materials are fully characterized, and Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.