Description

(2S)-2-(1-Methylethyl)Oxirane is a chiral epoxide compound, specifically the (S)-enantiomer of isobutylene oxide. This high-purity chiral building block is critical for introducing stereochemistry in complex organic syntheses, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require precise stereochemical control in their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the manufacture of chiral flavors, fragrances, and liquid crystals for electronic displays.
• Polymer Modification: Used to introduce chiral centers or reactive epoxide groups into polymer chains for specialty materials.

Basic Information

Product Name	(2S)-2-(1-Methylethyl)Oxirane
CAS No.	55123-01-8
Molecular Formula	C5H10O
Molecular Weight	86.13 g/mol
Synonyms	(S)-Isobutylene Oxide; (S)-2-Isopropyloxirane; (S)-2,2-Dimethyloxirane; (S)-1,2-Epoxy-2-methylpropane; (2S)-2-Isopropyloxirane; (S)-(-)-Isobutylene Oxide; L-Isobutylene Oxide; (S)-2-Methyl-1,2-epoxypropane
EINECS	Contact for details

Quality Control

Our (2S)-2-(1-Methylethyl)Oxirane is manufactured under strict quality management systems. Each batch is characterized by chiral HPLC or GC to ensure high enantiomeric excess (typically >98% ee) and chemical purity (>99%). Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment to guarantee reproducible performance in your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Due to its highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) when not in use to prevent polymerization or moisture ingress. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 99.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.