Description

2-(Cyclohexyloxy)-1,3,2-Dioxaborolane is a versatile cyclic boronic ester, a key intermediate in modern synthetic organic chemistry. Its primary value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics compared to its free acid counterpart. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for Suzuki-Miyaura cross-coupling reactions and other advanced synthetic transformations.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-boron linkages.
• Materials Science: Serves as a monomer or precursor in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex carbon-carbon bonds under mild conditions.
• Protecting Group Strategy: The cyclic dioxaborolane moiety acts as a protective group for boronic acids, preventing polymerization and improving solubility for specific reaction steps.

Basic Information

Product Name	2-(Cyclohexyloxy)-1,3,2-Dioxaborolane
CAS No.	55089-04-8
Molecular Formula	C8H15BO3
Molecular Weight	170.02 g/mol
Synonyms	Cyclohexyl Ethylene Glycol Boronate; 2-Cyclohexyloxy-1,3,2-dioxaborolane; Cyclohexyloxyboronic Acid Ethylene Ester; Cyclohexyl Ethylene Boronate; 1,3,2-Dioxaborolane, 2-(cyclohexyloxy)-; Cyclohexyl Boronic Acid Ethylene Ester; Cyclohexyloxy-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(Cyclohexyloxy)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.