Description

[1S,(+)]-1,2,3,4,4A,9,10,10Aα-Octahydro-6-Hydroxy-1,4Aβ-Dimethyl-7-(1-Methylethyl)-1β-Phenanthrenecarboxylic Acid is a high-purity, stereochemically defined diterpenoid carboxylic acid derivative. This compound is of significant interest for its role as a key synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries. The precise stereochemistry and functional groups make it a valuable building block for synthesizing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in steroid and terpenoid-based therapeutic areas.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in HPLC and LC-MS assays.
• Chemical Research: Employed in academic and industrial research for studying structure-activity relationships (SAR) and developing new synthetic methodologies for complex polycyclic systems.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Development: Investigated as a precursor for novel plant growth regulators or pesticides with specific stereochemical requirements.

Basic Information

Item	Detail
Product Name	[1S,(+)]-1,2,3,4,4A,9,10,10Aα-Octahydro-6-Hydroxy-1,4Aβ-Dimethyl-7-(1-Methylethyl)-1β-Phenanthrenecarboxylic Acid
CAS No.	55051-96-2
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	(+)-Abietic Acid derivative; (1S,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid; 1β-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10aα-octahydro-6-hydroxy-1,4aβ-dimethyl-7-(1-methylethyl)-, [1S-(1α,4aβ,10aα)]-; Diterpenoid acid intermediate; Hydroxyisopropylphenanthrenecarboxylic acid
EINECS	Contact for details

Quality Control

Our [1S,(+)]-1,2,3,4,4A,9,10,10Aα-Octahydro-6-Hydroxy-1,4Aβ-Dimethyl-7-(1-Methylethyl)-1β-Phenanthrenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet stringent specifications. Certificates of Analysis (COA) documenting all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.