Description

Phosphoric Acid 2-(Methoxyimino)Ethylbis(Trimethylsilyl) Ester is a specialized organosilicon-protected phosphoric acid derivative, a key intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile phosphorylating and silylating agent, offering controlled reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, where precise functional group manipulation is critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of nucleotide analogs, prodrugs, and other bioactive molecules requiring phosphate or phosphonate groups.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, insecticides, and plant growth regulators with phosphorous-containing backbones.
• Peptide & Oligonucleotide Chemistry: Employed as a phosphorylating agent in solid-phase and solution-phase synthesis to introduce phosphate esters.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, and flame-retardant materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organophosphorus chemistry and methodology development.
• Protecting Group Strategy: The trimethylsilyl (TMS) groups provide temporary protection for phosphate functionalities, enabling selective reactions in multi-step syntheses.

Basic Information

Product Name	Phosphoric Acid 2-(Methoxyimino)Ethylbis(Trimethylsilyl) Ester
CAS No.	55044-12-7
Molecular Formula	C9H24N1O5P1Si2
Molecular Weight	313.44 g/mol
Synonyms	2-(Methoxyimino)ethyl phosphorodiamidate bis(trimethylsilyl) ester; Phosphorodiamidic acid, 2-(methoxyimino)ethyl-, bis(trimethylsilyl) ester; O-[2-(Methoxyimino)ethyl]phosphorodiamidic acid bis(trimethylsilyl) ester; Bis(trimethylsilyl) 2-(methoxyimino)ethyl phosphoramidate; (2-(Methoxyimino)ethoxy)phosphonic acid diamide bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our production of Phosphoric Acid 2-(Methoxyimino)Ethylbis(Trimethylsilyl) Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.