Description

2,2-Difluoropent-4-Enoic Acid is a specialized fluorinated organic acid building block. This compound is valued for its unique structure, which incorporates both a carboxylic acid and a terminal alkene functional group, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides where the difluoro moiety can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers with tailored surface properties.
• Fluorine Chemistry: An essential building block in academic and industrial laboratories for exploring new fluorination reactions and creating fluorinated analogs of bioactive compounds.
• Peptide Mimetics: Utilized in the synthesis of fluorinated amino acid derivatives and peptide isosteres for medicinal chemistry applications.

Basic Information

Product Name	2,2-Difluoropent-4-Enoic Acid
CAS No.	55039-89-9
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	4-Pentenoic acid, 2,2-difluoro-; 2,2-Difluoro-4-pentenoic acid; 2,2-Difluoro-4-pentenoic acid; 2,2-Difluoropent-4-enoic acid; 2,2-Difluoro-4-pentenoic acid; 4-Pentenoic acid, 2,2-difluoro- (9CI); 2,2-Difluoropent-4-enoic acid
EINECS	Contact for details

Quality Control

Our 2,2-Difluoropent-4-Enoic Acid is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.